Anti-Human STAMBPL1/AMSHLP Polyclonal Antibody (HP089014)

Name: Anti-Human STAMBPL1/AMSHLP Polyclonal Antibody
Brand: abinScience
SKU: HP089014
Price: 168 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

50ug
100ug

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HP089014

Description

Anti-Human STAMBPL1/AMSHLP Polyclonal Antibody (HP089014) is a rabbit polyclonal antibody detecting STAMBPL1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human STAMBPL1/AMSHLP (Arg267-Arg436).

Target

AMSHLP, AMSH-LP, AMSH-like protease, STAMBPL1, STAM-binding protein-like 1, KIAA1373

Purification

Purified by antigen affinity column.

Accession

Q96FJ0

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

AMSH-like protease (STAMBPL1/AMSHLP) is a ~49 kDa protein. Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Acts as a positive regulator of the TORC1 signaling pathway by mediating 'Lys-63'-linked deubiquitination of SESN2, thereby inhibiting SESN2-interaction with the GATOR2 complex. Does not cleave 'Lys-48'-linked polyubiquitin chains.

1. Sato, Y. et al. (2008) Nature 455, 358-62. PMID: 18758443

2. Wang, D. et al. (2022) Molecular cell 82, 770-784.e9. PMID: 35114100

Note

For research use only.

Images

References

Datasheet

Anti-Human STAMBPL1/AMSHLP Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human STAMBPL1/AMSHLP Polyclonal Antibody (HP089014)

Overview

Images

References

Datasheet

SDS

Quick access

Contact Us