Anti-Human STEAP3 Polyclonal Antibody (HP251014)

Name: Anti-Human STEAP3 Polyclonal Antibody
Brand: abinScience
SKU: HP251014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HP251014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human STEAP3 (Lys30-Arg207).

Target

hpHyde, STEAP3, pHyde, Tumor suppressor-activated pathway protein 6, TSAP6, Metalloreductase STEAP3, Six-transmembrane epithelial antigen of prostate 3, hTSAP6, Dudulin-2

Purification

Purified by antigen affinity column.

Accession

Q658P3

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Metalloreductase STEAP3 is a ~54 kDa protein. Integral membrane protein that functions as a NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane. Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate. Can also reduce Cu(2+) to Cu(1+). Mediates efficient transferrin-dependent iron uptake in erythroid cells. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression.

1. Kleven, MD. et al. (2015) The Journal of biological chemistry 290, 22558-69. PMID: 26205815

2. Amzallag, N. et al. (2004) The Journal of biological chemistry 279, 46104-12. PMID: 15319436

3. Yu, X. et al. (2006) Cancer research 66, 4795-801. PMID: 16651434

Note

For research use only.

Images

References

Datasheet

Anti-Human STEAP3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human STEAP3 Polyclonal Antibody (HP251014)

Overview

Images

References

Datasheet

SDS

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