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Anti-Human STK26 Polyclonal Antibody (HP354014)

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Overview
Catalog No.HP354014
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human STK26 (Glu21-Gly298).
Target Serine/threonine-protein kinase MASK, Mammalian STE20-like protein kinase 4, MST3 and SOK1-related kinase, Serine/threonine-protein kinase 26, MST4, STE20-like kinase MST4, MST-4, MASK, STK26
Purification Purified by antigen affinity column.
Accession Q9P289
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Serine/threonine-protein kinase 26 (STK26) is a ~46 kDa protein. Serine/threonine-protein kinase that acts as a mediator of cell growth. Modulates apoptosis. In association with STK24 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation. Phosphorylates ATG4B at 'Ser-383', thereby increasing autophagic flux. Part of the striatin-interacting phosphatase and kinase (STRIPAK) complexes.

1. Lin, JL. et al. (2001) Oncogene 20, 6559-69. PMID: 11641781
2. Ma, X. et al. (2007) Molecular biology of the cell 18, 1965-78. PMID: 17360971
3. Mardakheh, FK. et al. (2016) Journal of cell science 129, 4466-4479. PMID: 27807006
4. Huang, T. et al. (2017) Cancer cell 32, 840-855.e8. PMID: 29232556
5. Goudreault, M. et al. (2009) Molecular & cellular proteomics : MCP 8, 157-71. PMID: 18782753
Note For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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Anti-Human STK26 Polyclonal Antibody

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