

| Catalog No. | HP880014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human STOML2 Polyclonal Antibody (HP880014) is a rabbit polyclonal antibody detecting STOML2 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, and Rat.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human STOML2 (Thr36-His181). | ||||||||
| Target | Stomatin-like protein 2, mitochondrial, Paratarg-7, SLP-2, STOML2, SLP2, EPB72-like protein 2, Paraprotein target 7 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9UJZ1 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Stomatin-like protein 2, mitochondrial (STOML2) is a ~38 kDa protein. Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. | ||||||||
| Note | For research use only. |
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