Anti-Human STX1A Recombinant Antibody (SAA1684) (HS851013)

Name: Anti-Human STX1A Recombinant Antibody (SAA1684)
Brand: abinScience
SKU: HS851013
Price: 196 USD
Availability: InStock

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100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HS851013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1684

Clonality

Monoclonal

Target

STX1A, STX1, Neuron-specific antigen HPC-1, Syntaxin-1A

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q16623

RRID

Anti-Human STX1A Antibody (SAA1684) (abinScience Cat# HS851013, RRID:AB_3727445)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Syntaxin-1A (STX1A) is a ~33 kDa protein. Plays an essential role in hormone and neurotransmitter calcium-dependent exocytosis and endocytosis. Part of the SNARE (Soluble NSF Attachment Receptor) complex composed of SNAP25, STX1A and VAMP2 which mediates the fusion of synaptic vesicles with the presynaptic plasma membrane. STX1A and SNAP25 are localized on the plasma membrane while VAMP2 resides in synaptic vesicles. The pairing of the three SNAREs from the N-terminal SNARE motifs to the C-terminal anchors leads to the formation of the SNARE complex, which brings membranes into close proximity and results in final fusion. Participates in the calcium-dependent regulation of acrosomal exocytosis in sperm.

1. Craig, TJ. et al. (2015) Scientific reports 5, 17669. PMID: 26635000

2. Rodríguez, F. et al. (2012) The Journal of biological chemistry 287, 43825-39. PMID: 23091057

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human STX1A Antibody (SAA1684)

References

Datasheet

Anti-Human STX1A Recombinant Antibody (SAA1684).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human STX1A Recombinant Antibody (SAA1684) (HS851013)

Overview

Images

References

Datasheet

SDS

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