Anti-Human SULT2A1 Polyclonal Antibody (HB426014)

Name: Anti-Human SULT2A1 Polyclonal Antibody
Brand: abinScience
SKU: HB426014
Price: 96 USD
Availability: InStock

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Overview

Catalog No.

HB426014

Description

Anti-Human SULT2A1 Polyclonal Antibody (HB426014) is a rabbit polyclonal antibody detecting Sulfotransferase 2A1; ST2A1; 2.8.2.2; Bile salt sulfotransferase; 2.8.2.14; Dehydroepiandrosterone sulfotransferase; DHEA-ST; DHEA-ST8; Hydroxysteroid Sulfotransferase; HST; ST2; SULT2A3; SULT2A1; HST; STD in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant human SULT2A1 (Met1-Glu285).

Target

Sulfotransferase 2A1; ST2A1; 2.8.2.2; Bile salt sulfotransferase; 2.8.2.14; Dehydroepiandrosterone sulfotransferase; DHEA-ST; DHEA-ST8; Hydroxysteroid Sulfotransferase; HST; ST2; SULT2A3; SULT2A1; HST; STD

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

Q06520

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Sulfotransferase 2A1 (SULT2A1) is a ~33 kDa protein. Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands. Mediates the sulfation of a wide range of steroids and sterols, including pregnenolone, androsterone, DHEA, bile acids, cholesterol and as well many xenobiotics that contain alcohol and phenol functional groups. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Plays an important role in maintening steroid and lipid homeostasis. Plays a key role in bile acid metabolism, mediating formation of 3-sulfated bile acids.

1. Chang, HJ. et al. (2004) The Journal of biological chemistry 279, 2689-96. PMID: 14573603

2. Lu, LY. et al. (2008) Molecular pharmacology 73, 660-8. PMID: 18042734

3. Cook, IT. et al. (2009) Drug metabolism and disposition: the biological fate of chemicals 37, 2069-78. PMID: 19589875

4. Huang, J. et al. (2010) Xenobiotica; the fate of foreign compounds in biological systems 40, 184-94. PMID: 20102295

5. Gulcan, HO. et al. (2011) Archives of biochemistry and biophysics 507, 232-40. PMID: 21187059

6. Radominska, A. et al. (1990) The Biochemical journal 272, 597-604. PMID: 2268288

7. Abunnaja, MS. et al. (2018) Biochemistry and cell biology = Biochimie et biologie cellulaire 96, 655-662. PMID: 29671343

8. Comer, KA. et al. (1993) The Biochemical journal 289 ( Pt 1), 233-40. PMID: 7678732

9. Glatt, H. et al. (1994) Mutagenesis 9, 553-7. PMID: 7854148

Note

For research use only

Images

Western blot

Western blot analysis was performed using anti-SULT2A1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: HepG2 cell lysate

References

Datasheet

Anti-Human SULT2A1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Anti-Human SULT2A1 Polyclonal Antibody (HB426014)

Overview

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References

Datasheet

SDS

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