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Anti-Human SULT2B1 Polyclonal Antibody (HT231014)

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Overview
Catalog No.HT231014
Description
Anti-Human SULT2B1 Polyclonal Antibody (HT231014) is a rabbit polyclonal antibody detecting SULT2B1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human SULT2B1 (Gly29-Gly303).
Target Sulfotransferase 2B1, 2.8.2.2, Alcohol sulfotransferase, Hydroxysteroid sulfotransferase 2, Sulfotransferase family 2B member 1, Sulfotransferase family cytosolic 2B member 1, ST2B1, SULT2B1, HSST2
Purification Purified by antigen affinity column.
Accession O00204
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Sulfotransferase 2B1 (SULT2B1) is a ~41 kDa protein. Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation. Responsible for the sulfation of cholesterol. Catalyzes sulfation of the 3beta-hydroxyl groups of steroids, such as, pregnenolone and dehydroepiandrosterone (DHEA). Preferentially sulfonates cholesterol, while it also has significant activity with pregnenolone and DHEA. Plays a role in epidermal cholesterol metabolism and in the regulation of epidermal proliferation and differentiation.

1. Fuda, H. et al. (2002) The Journal of biological chemistry 277, 36161-6. PMID: 12145317
2. Cook, IT. et al. (2009) Drug metabolism and disposition: the biological fate of chemicals 37, 2069-78. PMID: 19589875
3. He, D. et al. (2006) Drug metabolism and disposition: the biological fate of chemicals 34, 1749-55. PMID: 16855051
4. Salman, ED. et al. (2011) The Journal of steroid biochemistry and molecular biology 127, 315-23. PMID: 21855633
5. Her, C. et al. (1998) Genomics 53, 284-95. PMID: 9799594
6. Heinz, L. et al. (2017) American journal of human genetics 100, 926-939. PMID: 28575648
Note For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human SULT2B1 Polyclonal Antibody

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