

| Catalog No. | HF940014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human TAF5L Polyclonal Antibody (HF940014) is a rabbit polyclonal antibody detecting TAF5L in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human TAF5L (Thr257-His589). | ||||||||
| Target | TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L, TAF5L, PCAF-associated factor 65 beta, PAF65-beta, TAF5L, PAF65B | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O75529 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (TAF5L) is a ~66 kDa protein. Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex (Probable). With TAF6L, acts as an epigenetic regulator essential for somatic reprogramming. Regulates target genes through H3K9ac deposition and MYC recruitment which trigger MYC regulatory network to orchestrate gene expression programs to control embryonic stem cell state. | ||||||||
| Note | For research use only. |
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