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Anti-Human TBC1D23 Polyclonal Antibody (HP216014)

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Overview
Catalog No.HP216014
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human TBC1D23 (Gly15-Lys306).
Target NS4ATP1, TBC1D23, TBC1 domain family member 23, HCV non-structural protein 4A-transactivated protein 1
Purification Purified by antigen affinity column.
Accession Q9NUY8
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

TBC1 domain family member 23 (TBC1D23) is a ~78 kDa protein. Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles. Together with WDR11 complex facilitates the golgin-mediated capture of vesicles generated using AP-1. Plays a role in brain development, including in cortical neuron positioning.

1. Ivanova, EL. et al. (2017) American journal of human genetics 101, 428-440. PMID: 28823707
2. Shin, JJH. et al. (2017) Nature cell biology 19, 1424-1432. PMID: 29084197
3. Navarro Negredo, P. et al. (2018) Nature communications 9, 596. PMID: 29426865
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human TBC1D23 Polyclonal Antibody

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