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Anti-Human TBL1X Polyclonal Antibody (HF868014)

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Overview
Catalog No.HF868014
Description
Anti-Human TBL1X Polyclonal Antibody (HF868014) is a rabbit polyclonal antibody detecting TBL1X. Suitable for Mouse and Human.
Highlights
  • Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human TBL1X (Val218-Lys577).
Target F-box-like/WD repeat-containing protein TBL1X, SMAP55, TBL1, TBL1X, Transducin beta-like protein 1X, Transducin-beta-like protein 1, X-linked
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession O60907
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

F-box-like/WD repeat-containing protein TBL1X is a ~62 kDa protein. F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.

1. Perissi, V. et al. (2004) Cell 116, 511-26. PMID: 14980219
2. Oberoi, J. et al. (2011) Nature structural & molecular biology 18, 177-84. PMID: 21240272
Note For research use only
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Formula
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