

| Catalog No. | HT239014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human TBX1 Polyclonal Antibody (HT239014) is a rabbit polyclonal antibody detecting TBX1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human TBX1 (Ala108-Pro290). | ||||||||
| Target | T-box transcription factor TBX1, T-box protein 1, Testis-specific T-box protein, TBX1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O43435 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | T-box transcription factor TBX1 is a ~43 kDa protein. Transcription factor that plays a key role in cardiovascular development by promoting pharyngeal arch segmentation during embryonic development. Also involved in craniofacial muscle development. Together with NKX2-5, acts as a regulator of asymmetric cardiac morphogenesis by promoting expression of PITX2. Acts upstream of TBX1 for the formation of the thymus and parathyroid glands from the third pharyngeal pouch. Required for hair follicle stem cell self-renewal. 1. Sinha, S. et al. (2000) Gene 258, 15-29. PMID: 11111039 2. El Omari, K. et al. (2012) Proteins 80, 655-60. PMID: 22095455 | ||||||||
| Note | For research use only. |
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