Anti-Human TCIRG1 Polyclonal Antibody (HC655014)

Name: Anti-Human TCIRG1 Polyclonal Antibody
Brand: abinScience
SKU: HC655014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HC655014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human TCIRG1 (Met1-Glu385).

Target

TCIRG1, Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3, V-ATPase 116 kDa subunit a3, V-type proton ATPase 116 kDa subunit a3, ATP6V0A3, ATP6N1C, Osteoclastic proton pump 116 kDa subunit, TIRC7, T-cell immune response cDNA7 protein, T-cell immune regulator 1, OC-116 kDa, OC116

Purification

Purified by antigen affinity column.

Accession

Q13488

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

V-type proton ATPase 116 kDa subunit a 3 (TCIRG1/TIRC7) is a ~92 kDa protein. Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Seems to be directly involved in T-cell activation.

1. Heinemann, T. et al. (1999) Genomics 57, 398-406. PMID: 10329006

Note

For research use only.

Images

References

Datasheet

Anti-Human TCIRG1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human TCIRG1 Polyclonal Antibody (HC655014)

Overview

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References

Datasheet

SDS

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