

| Catalog No. | HP573014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human TESC Polyclonal Antibody (HP573014) is a rabbit polyclonal antibody detecting TESC in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human TESC (Met1-His214). | ||||||||
| Target | TSC, TESC, CHP3, Calcineurin B homologous protein 3, Tescalcin | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q96BS2 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Calcineurin B homologous protein 3 (TESC) is a ~24 kDa protein. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. | ||||||||
| Note | For research use only. |
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