

| Catalog No. | HA351014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human TESPA1 Polyclonal Antibody (HA351014) is a rabbit polyclonal antibody detecting Protein TESPA1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human TESPA1 (Ser148-Asp335). | ||||||||
| Target | Protein TESPA1, Thymocyte-expressed positive selection-associated protein 1, TESPA1, KIAA0748, HSPC257 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | A2RU30 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Protein TESPA1 is a ~59 kDa protein. Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development. Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release and mitochondrial Ca(2+) uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment. | ||||||||
| Note | For research use only. |
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