

| Catalog No. | HP170014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human TEX10 (Lys60-Ser220). | ||||||||
| Target | TEX10, Testis-expressed protein 10 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9NXF1 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Testis-expressed protein 10 (TEX10) is a ~105 kDa protein. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes. Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit. 1. Fanis, P. et al. (2012) Molecular & cellular proteomics : MCP 11, 1263-73. PMID: 22872859 2. Finkbeiner, E. et al. (2011) The EMBO journal 30, 1067-78. PMID: 21326211 | ||||||||
| Note | For research use only. |
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