

| Catalog No. | HC653014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human TFCP2 (Gln68-Gln266). | ||||||||
| Target | SEF, LSF, SAA3 enhancer factor, TFCP2, Transcription factor LSF, Alpha-globin transcription factor CP2 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q12800 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Alpha-globin transcription factor CP2 (TFCP2) is a ~57 kDa protein. Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1. Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter. | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-Human TFCP2 polyclonal antibody at 1ug/mL on recombinant Human TFCP2 (Catalog No. HC653012).
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