

| Catalog No. | HF782013 | ||||
|---|---|---|---|---|---|
| Description |
Anti-Human TIMP1 Recombinant Antibody (2PC10) (HF782013) is a mouse monoclonal antibody detecting TIMP1 in Blocking, ELISA. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||
| Applications | Blocking, ELISA | ||||
| Host species | Mouse | ||||
| Clonality | Monoclonal | ||||
| Isotype | IgG2a, kappa | ||||
| Clone ID | 2PC10 | ||||
| Target | Erythroid-potentiating activity, TIMP, EPA, TIMP1, Metalloproteinase inhibitor 1, TIMP-1, Fibroblast collagenase inhibitor, Collagenase inhibitor, CLGI, Tissue inhibitor of metalloproteinases 1 | ||||
| Endotoxin level | < 10 EU/mg as determined by LAL method. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | P01033 | ||||
| RRID | Anti-Human TIMP1 Antibody (2PC10) (abinScience Cat# HF782013, RRID:AB_3725813) |
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| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Metalloproteinase inhibitor 1 (TIMP1) is a ~23 kDa protein. Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. | ||||
| Note | For research use only. | ||||
| Isotype Control | Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023) |

SDS-PAGE for Anti-Human TIMP1 Antibody (2PC10)



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