Anti-Human TM4SF20 Recombinant Antibody (SAA1694) (HS891013)

Name: Anti-Human TM4SF20 Recombinant Antibody (SAA1694)
Brand: abinScience
SKU: HS891013
Price: 110 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HS891013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1694

Clonality

Monoclonal

Target

Transmembrane 4 L6 family member 20, TM4SF20

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q53R12

RRID

Anti-Human TM4SF20 Antibody (SAA1694) (abinScience Cat# HS891013, RRID:AB_3727455)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Transmembrane 4 L6 family member 20 (TM4SF20) is a ~25 kDa protein. Polytopic transmembrane protein that inhibits regulated intramembrane proteolysis (RIP) of CREB3L1, inhibiting its activation and the induction of collagen synthesis. In response to ceramide, which alters TM4SF20 membrane topology, stimulates RIP activation of CREB3L1. Ceramide reverses the direction through which transmembrane helices are translocated into the endoplasmic reticulum membrane during translation of TM4SF20, this mechanism is called 'regulated alternative translocation' (RAT) and regulates the function of the transmembrane protein.

1. Chen, Q. et al. (2014) PloS one 9, e108528. PMID: 25310401

2. Chen, Q. et al. (2016) Molecular cell 63, 567-578. PMID: 27499293

Note

For research use only.

Isotype Control

Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)

Images

SDS-PAGE

SDS-PAGE for Anti-Human TM4SF20 Antibody (SAA1694)

References

Datasheet

Anti-Human TM4SF20 Recombinant Antibody (SAA1694).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human TM4SF20 Recombinant Antibody (SAA1694) (HS891013)

Overview

Images

References

Datasheet

SDS

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