Anti-Human TMEM106B Recombinant Antibody (SAA1912) (HA136013)

Name: Anti-Human TMEM106B Recombinant Antibody (SAA1912)
Brand: abinScience
SKU: HA136013
Price: 110 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HA136013

Species reactivity

Human, Mouse

Applications

ELISA, FCM, SPR

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1912

Clonality

Monoclonal

Target

TMEM106B, Transmembrane protein 106B

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9NUM4, Q80X71

RRID

Anti-Human TMEM106B Antibody (SAA1912) (abinScience Cat# HA136013, RRID:AB_3727676)
_x005F_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Transmembrane protein 106B (TMEM106B) is a ~31 kDa protein. In neurons, involved in the transport of late endosomes/lysosomes. May be involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking. May act as a molecular brake for retrograde transport of late endosomes/lysosomes, possibly via its interaction with MAP6. In motoneurons, may mediate the axonal transport of lysosomes and axonal sorting at the initial segment. It remains unclear whether TMEM106B affects the transport of moving lysosomes in the anterograde or retrograde direction in neurites and whether it is important in the sorting of lysosomes in axons or in dendrites.

1. Stagi, M. et al. (2014) Molecular and cellular neurosciences 61, 226-40. PMID: 25066864

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human TMEM106B Antibody (SAA1912)

References

Datasheet

Anti-Human TMEM106B Recombinant Antibody (SAA1912).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human TMEM106B Recombinant Antibody (SAA1912) (HA136013)

Overview

Images

References

Datasheet

SDS

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