

| Catalog No. | HB401014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human TMEM108 Polyclonal Antibody (HB401014) is a rabbit polyclonal antibody detecting Transmembrane protein 108; Retrolinkin; TMEM108; KIAA1690; RTLN; UNQ1875/PRO4318 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant human TMEM108 (Glu31-Pro169). | ||||||||
| Target | Transmembrane protein 108; Retrolinkin; TMEM108; KIAA1690; RTLN; UNQ1875/PRO4318 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q6UXF1 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Transmembrane protein 108 (TMEM108) is a ~59 kDa protein. Transmembrane protein required for proper cognitive functions. Involved in the development of dentate gyrus (DG) neuron circuitry, is necessary for AMPA receptors surface expression and proper excitatory postsynaptic currents of DG granule neurons. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport. Through the interaction with DST, mediates the docking of the dynein/dynactin motor complex to vesicle cargos for retrograde axonal transport. In hippocampal neurons, required for BDNF-dependent dendrite outgrowth. | ||||||||
| Note | For research use only |
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