

| Catalog No. | HA247014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human TNIK Polyclonal Antibody (HA247014) is a rabbit polyclonal antibody detecting TNIK in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human TNIK (Glu1038-Trp1360). | ||||||||
| Target | TRAF2 and NCK-interacting protein kinase, 2.7.11.1, TNIK, KIAA0551 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9UKE5 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | TRAF2 and NCK-interacting protein kinase (TNIK) is a ~154 kDa protein. Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. 1. Meng, Z. et al. (2015) Nature communications 6, 8357. PMID: 26437443 | ||||||||
| Note | For research use only. |



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