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Anti-Human TNS1 Polyclonal Antibody (HP456014)

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Overview
Catalog No.HP456014
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human TNS1 (Ser4-Gly307).
Target TNS1, Tensin-1, TNS
Purification Purified by antigen affinity column.
Accession Q9HBL0
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Tensin-1 (TNS1) is a ~197 kDa protein. May act as a protein phosphatase and/or a lipid phosphatase (Probable). Involved in fibrillar adhesion formation. Essential for myofibroblast differentiation and myofibroblast-mediated extracellular matrix deposition. Enhances RHOA activation in the presence of DLC1. Plays a role in cell polarization and migration.

1. Brunner, M. et al. (2011) The Journal of cell biology 194, 307-22. PMID: 21768292
2. Bernau, K. et al. (2017) American journal of respiratory cell and molecular biology 56, 465-476. PMID: 28005397
3. Shih, YP. et al. (2015) Biochimica et biophysica acta 1853, 3258-65. PMID: 26427649
4. Hall, EH. et al. (2009) The Journal of biological chemistry 284, 34713-22. PMID: 19826001
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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C₁ × V₁ = C₂ × V₂
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C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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Anti-Human TNS1 Polyclonal Antibody

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