Anti-Human TOR1A/Torsin-1A/DQ2 Recombinant Antibody (SAA1807) (HT415013)

Name: Anti-Human TOR1A/Torsin-1A/DQ2 Recombinant Antibody (SAA1807)
Brand: abinScience
SKU: HT415013
Price: 196 USD
Availability: InStock

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100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HT415013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1807

Clonality

Monoclonal

Target

Torsin-1A, TOR1A, Torsin family 1 member A, DQ2, Dystonia 1 protein, TORA, TA, Torsin ATPase-1A, DYT1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O14656

RRID

Anti-Human TOR1A/Torsin-1A/DQ2 Antibody (SAA1807) (abinScience Cat# HT415013, RRID:AB_3727569)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Torsin-1A (TOR1A/DQ2) is a ~37 kDa protein. Protein with chaperone functions important for the control of protein folding, processing, stability and localization as well as for the reduction of misfolded protein aggregates. Involved in the regulation of synaptic vesicle recycling, controls STON2 protein stability in collaboration with the COP9 signalosome complex (CSN). In the nucleus, may link the cytoskeleton with the nuclear envelope, this mechanism seems to be crucial for the control of nuclear polarity, cell movement and, specifically in neurons, nuclear envelope integrity. Participates in the cellular trafficking and may regulate the subcellular location of multipass membrane proteins such as the dopamine transporter SLC6A3, leading to the modulation of dopamine neurotransmission. In the endoplasmic reticulum, plays a role in the quality control of protein folding by increasing clearance of misfolded proteins such as SGCE variants or holding them in an intermediate state for proper refolding.

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human TOR1A/Torsin-1A/DQ2 Antibody (SAA1807)

References

Datasheet

Anti-Human TOR1A/Torsin-1A/DQ2 Recombinant Antibody (SAA1807).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human TOR1A/Torsin-1A/DQ2 Recombinant Antibody (SAA1807) (HT415013)

Overview

Images

References

Datasheet

SDS

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