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Anti-Human TPP2 Polyclonal Antibody (HB208014)

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Overview
Catalog No.HB208014
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human TPP2 (Thr21-Ala489).
Target Tripeptidyl aminopeptidase, TPP2, Tripeptidyl-peptidase 2, TPP-2, TPP-II, Tripeptidyl-peptidase II
Purification Purified by antigen affinity column.
Accession P29144
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Tripeptidyl-peptidase 2 (TPP2) is a ~138 kDa protein. Cytosolic tripeptidyl-peptidase that releases N-terminal tripeptides from polypeptides and is a component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. It plays an important role in intracellular amino acid homeostasis. Stimulates adipogenesis.

1. Lu, W. et al. (2014) Cell 159, 1578-90. PMID: 25525876
2. Reinthaler, EM. et al. (2018) Neurology. Genetics 4, e285. PMID: 30533531
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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C₂ (Working Conc.)
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Anti-Human TPP2 Polyclonal Antibody

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