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Anti-Human TRABD2A Polyclonal Antibody (HA378024)

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Overview
Catalog No.HA378024
Description
Anti-Human TRABD2A Polyclonal Antibody (HA378024) is a rabbit polyclonal antibody detecting TRABD2A. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human TRABD2A (Ala20-His360).
Target C2orf89, EC:3.4.-.-, Metalloprotease TIKI1, TIKI1, TRAB domain-containing protein 2A, TRABD2A
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q86V40
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Metalloprotease TIKI1 (TRABD2A) is a ~57 kDa protein. Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation.

Note For research use only
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