Anti-Human TRIAP1 Polyclonal Antibody (HT270014)

Name: Anti-Human TRIAP1 Polyclonal Antibody
Brand: abinScience
SKU: HT270014
Price: 168 USD
Availability: InStock

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References
Datasheet
SDS

Overview

Catalog No.

HT270014

Description

Anti-Human TRIAP1 Polyclonal Antibody (HT270014) is a rabbit polyclonal antibody detecting TRIAP1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human TRIAP1 (Asn2-Ser76).

Target

TP53-regulated inhibitor of apoptosis 1, Protein 15E1.1, WF-1, p53-inducible cell-survival factor, p53CSV, TRIAP1, 15E1.1, HSPC132

Purification

Purified by antigen affinity column.

Accession

O43715

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

TP53-regulated inhibitor of apoptosis 1 (TRIAP1) is a ~8 kDa protein. Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis.

1. Potting, C. et al. (2013) Cell metabolism 18, 287-95. PMID: 23931759

2. Miliara, X. et al. (2015) EMBO reports 16, 824-35. PMID: 26071602

3. Park, WR. et al. (2005) Cancer research 65, 1197-206. PMID: 15735003

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Human TRIAP1 polyclonal antibody at 1ug/mL on recombinant Human TRIAP1 (Catalog No. HT270012).

References

Datasheet

Anti-Human TRIAP1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human TRIAP1 Polyclonal Antibody (HT270014)

Overview

Images

References

Datasheet

SDS

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