

| Catalog No. | HP355014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human TRIM46 (Thr525-Lys745). | ||||||||
| Target | Tripartite, fibronectin type-III and C-terminal SPRY motif protein, GeneY, Gene Y protein, Tripartite motif-containing protein 46, TRIM46, TRIFIC | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q7Z4K8 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Tripartite motif-containing protein 46 (TRIM46) is a ~83 kDa protein. Microtubule-associated protein that is involved in the formation of parallel microtubule bundles linked by cross-bridges in the proximal axon. Required for the uniform orientation and maintenance of the parallel microtubule fascicles, which are important for efficient cargo delivery and trafficking in axons. Thereby also required for proper axon specification, the establishment of neuronal polarity and proper neuronal migration. | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-TRIM46 polyclonal antibody at 1µg/ml on various samples.
Lane 1: Mouse brain lysate
Lane 2: Rat brain lysate
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