Anti-Human TRIO Recombinant Antibody (SAA1532) (HF906013)

Name: Anti-Human TRIO Recombinant Antibody (SAA1532)
Brand: abinScience
SKU: HF906013
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HF906013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1532

Clonality

Monoclonal

Target

TRIO, Triple functional domain protein, PTPRF-interacting protein

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O75962

RRID

Anti-Human TRIO Antibody (SAA1532) (abinScience Cat# HF906013, RRID:AB_3727293)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Triple functional domain protein (TRIO) is a ~346 kDa protein. Guanine nucleotide exchange factor (GEF) for RHOA and RAC1 GTPases. Involved in coordinating actin remodeling, which is necessary for cell migration and growth. Plays a key role in the regulation of neurite outgrowth and lamellipodia formation. In developing hippocampal neurons, limits dendrite formation, without affecting the establishment of axon polarity. Once dendrites are formed, involved in the control of synaptic function by regulating the endocytosis of AMPA-selective glutamate receptors (AMPARs) at CA1 excitatory synapses.

1. Deinhardt, K. et al. (2011) Science signaling 4, ra82. PMID: 22155786

2. Pengelly, RJ. et al. (2016) Journal of medical genetics 53, 735-742. PMID: 27418539

3. Debant, A. et al. (1996) Proceedings of the National Academy of Sciences of the United States of America 93, 5466-71. PMID: 8643598

4. Seipel, K. et al. (1999) Journal of cell science 112 ( Pt 12), 1825-34. PMID: 10341202

5. Barbosa, S. et al. (2020) American journal of human genetics 106, 338-355. PMID: 32109419

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human TRIO Antibody (SAA1532)

References

Datasheet

Anti-Human TRIO Recombinant Antibody (SAA1532).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human TRIO Recombinant Antibody (SAA1532) (HF906013)

Overview

Images

References

Datasheet

SDS

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