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Anti-Human TSHZ3 Polyclonal Antibody (HD311014)

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Overview
Catalog No.HD311014
Description
Anti-Human TSHZ3 Polyclonal Antibody (HD311014) is a rabbit polyclonal antibody detecting TSHZ3. Suitable for Human, Mouse, and Rat.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human TSHZ3 (Trp898-Gln1081).
Target KIAA1474, TSH3, TSHZ3, Teashirt homolog 3, ZNF537, Zinc finger protein 537
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q63HK5
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Teashirt homolog 3 (TSHZ3) is a ~118 kDa protein. Transcriptional regulator involved in developmental processes. Functions in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). Regulates the development of neurons involved in both respiratory rhythm and airflow control.

1. Kajiwara, Y. et al. (2009) PloS one 4, e5071. PMID: 19343227
Note For research use only
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Formula
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Anti-Human TSHZ3 Polyclonal Antibody

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