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Anti-Human TSPAN14 Polyclonal Antibody (HD404014)

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Overview
Catalog No.HD404014
Description
Anti-Human TSPAN14 Polyclonal Antibody (HD404014) is a rabbit polyclonal antibody detecting TSPAN14. Suitable for Mouse and Human.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human TSPAN14 (Leu114-Asn232).
Target DC-TM4F2, TM4SF14, TSPAN14, Tetraspanin-14, Transmembrane 4 superfamily member 14, Tspan-14
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q8NG11
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Tetraspanin-14 (TSPAN14) is a ~30 kDa protein. Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell surface as well as substrate specificity. Different TspanC8/ADAM10 complexes have distinct substrates. Negatively regulates ADAM10-mediated cleavage of GP6. Promotes ADAM10-mediated cleavage of CDH5.

1. Haining, EJ. et al. (2012) The Journal of biological chemistry 287, 39753-65. PMID: 23035126
2. Noy, PJ. et al. (2016) The Journal of biological chemistry 291, 3145-57. PMID: 26668317
3. Jouannet, S. et al. (2016) Cellular and molecular life sciences : CMLS 73, 1895-915. PMID: 26686862
4. Lipper, CH. et al. (2023) Cell 186, 3632-3641.e10. PMID: 37516108
Note For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human TSPAN14 Polyclonal Antibody

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