

| Catalog No. | HA218013 | ||||
|---|---|---|---|---|---|
| Species reactivity | Human | ||||
| Applications | ELISA | ||||
| Host species | Mouse | ||||
| Isotype | IgG2a, kappa | ||||
| Clone ID | SAA1856 | ||||
| Clonality | Monoclonal | ||||
| Target | PEN, Penumbra, TSPAN33, Tetraspanin-33, hPen, Tspan-33, Proerythroblast new membrane | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | Q86UF1 | ||||
| RRID | Anti-Human TSPAN33 Antibody (SAA1856) (abinScience Cat# HA218013, RRID:AB_3727619) |
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| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Tetraspanin-33 (TSPAN33) is a ~31 kDa protein. Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell surface as well as substrate specificity. Different TspanC8/ADAM10 complexes have distinct substrates. Plays an important role in normal erythropoiesis. It has a role in the differentiation of erythroid progenitors. 1. Jouannet, S. et al. (2016) Cellular and molecular life sciences : CMLS 73, 1895-915. PMID: 26686862 2. Shah, J. et al. (2018) Cell reports 25, 2132-2147.e7. PMID: 30463011 3. Lipper, CH. et al. (2023) Cell 186, 3632-3641.e10. PMID: 37516108 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human TSPAN33 Antibody (SAA1856)
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