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Anti-Human TTC4 Polyclonal Antibody (HF706014)

Anti-Human TTC4 Polyclonal Antibody
Anti-Human TTC4 Polyclonal Antibody
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Overview
Catalog No.HF706014
Description
Anti-Human TTC4 Polyclonal Antibody (HF706014) is a rabbit polyclonal antibody detecting TTC4 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human TTC4 (Ile231-Arg387).
Target Tetratricopeptide repeat protein 4, TPR repeat protein 4, TTC4, My044
Purification Purified by antigen affinity column.
Accession O95801
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Hsp70/Hsp90 co-chaperone CNS1 homolog (TTC4) is a ~44 kDa protein. Co-chaperone that recruits molecular chaperones Hsp90 (HSC82 and HSP82) and Hsp70 (SSA1) to nascent polypeptides, facilitating their proper folding into functional proteins. Client proteins include eukaryotic elongation factor eEF2, a key player in cellular translation. Stimulates SSA1 ATPase activity, but not Hsp90 ATPase activity. Promotes Sendai virus (SeV)-induced host cell innate immune responses.

1. Crevel, G. et al. (2008) PloS one 3, e0001737. PMID: 18320024
2. Shang, J. et al. (2018) Proteomics 18. PMID: 29251827
Note For research use only.
Images
  • Anti-Human TTC4 Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-TTC4 polyclonal antibody at TTC4 on various samples.
    Lane 1: 293T cell lysate

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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