Anti-Human TUBGCP3 Polyclonal Antibody (HP130014)

Name: Anti-Human TUBGCP3 Polyclonal Antibody
Brand: abinScience
SKU: HP130014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HP130014

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human TUBGCP3 (Ile245-Ser554).

Target

Gamma-ring complex protein 104 kDa, GCP-3, hGrip104, Spindle pole body protein Spc98 homolog, GCP3, h104p, Gamma-tubulin complex component 3, hGCP3, TUBGCP3, hSpc98

Purification

Purified by antigen affinity column.

Accession

Q96CW5

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Gamma-tubulin complex component 3 (TUBGCP3) is a ~103 kDa protein. Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation.

1. Brito, C. et al. (2024) Science (New York, N.Y.) 383, 870-876. PMID: 38305685

2. Aher, A. et al. (2024) Nature structural & molecular biology 31, 1124-1133. PMID: 38609661

3. Serna, M. et al. (2024) Developmental cell 59, 3175-3188.e8. PMID: 39321809

4. Murphy, SM. et al. (1998) The Journal of cell biology 141, 663-74. PMID: 9566967

Note

For research use only.

Images

References

Datasheet

Anti-Human TUBGCP3 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human TUBGCP3 Polyclonal Antibody (HP130014)

Overview

Images

References

Datasheet

SDS

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