

| Catalog No. | HB200014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human TYR Polyclonal Antibody (HB200014) is a rabbit polyclonal antibody detecting TYR in ELISA, IHC, WB. Suitable for Mus musculus, Human, Felis catus, and Bovine.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human TYR (His19-Ser476). | ||||||||
| Target | TYR | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P14679 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Alternate Names | Tyrosinase, 1.14.18.1, LB24-AB, Monophenol monooxygenase, SK29-AB, Tumor rejection antigen AB, TYR | ||||||||
| Background | Tyrosinase is a ~60 kDa protein. This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone. 1. Lai, X. et al. (2017) Angewandte Chemie (International ed. in English) 56, 9812-9815. PMID: 28661582 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-TYR polyclonal antibody at 1ug/mL on various samples.
Lane 1: Rat lung lysate


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