Anti-Human TYRP1 Recombinant Antibody (TA99) (HB884013)

Name: Anti-Human TYRP1 Recombinant Antibody (TA99)
Brand: abinScience
SKU: HB884013
Price: 126 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

20ug
50ug
100ug
1mg

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HB884013

Species reactivity

Human, Mouse, Rat

Applications

IF, WB

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

TA99

Clonality

Monoclonal

Target

5, 6-dihydroxyindole-2-carboxylic acid oxidase, Glycoprotein 75, CAS2, TYRP1, TRP-1, TYRRP, TRP1, Catalase B, TYRP, Melanoma antigen gp75, TRP, DHICA oxidase, Tyrosinase-related protein 1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P17643

RRID

Anti-Human TYRP1 Antibody (TA99) (abinScience Cat# HB884013, RRID:AB_3725672)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

5,6-dihydroxyindole-2-carboxylic acid oxidase (TYRP1) is a ~60 kDa protein. Plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid in the presence of bound Cu(2+) ions, but not in the presence of Zn(2+). May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin.

1. Rooryck, C. et al. (2006) Pigment cell research 19, 239-42. PMID: 16704458

2. Kenny, EE. et al. (2012) Science (New York, N.Y.) 336, 554. PMID: 22556244

3. Simeonov, DR. et al. (2013) Human mutation 34, 827-35. PMID: 23504663

4. Lai, X. et al. (2017) Angewandte Chemie (International ed. in English) 56, 9812-9815. PMID: 28661582

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human TYRP1 Antibody (TA99).

References

Datasheet

Anti-Human TYRP1 Recombinant Antibody (TA99).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human TYRP1 Recombinant Antibody (TA99) (HB884013)

Overview

Images

References

Datasheet

SDS

Quick access

Contact Us