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Anti-Human UGDH Polyclonal Antibody (HA400014)

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Overview
Catalog No.HA400014
Description
Anti-Human UGDH Polyclonal Antibody (HA400014) is a rabbit polyclonal antibody detecting UGDH. Suitable for Human, Rat, and Mouse.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human UGDH (Met1-Val494).
Target EC:1.1.1.22, UDP-Glc dehydrogenase, UDP-GlcDH, UDP-glucose 6-dehydrogenase, UDPGDH, UGDH
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession O60701
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

UDP-glucose 6-dehydrogenase (UGDH) is a ~55 kDa protein. Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans. Required for the biosynthesis of chondroitin sulfate and heparan sulfate. Required for embryonic development via its role in the biosynthesis of glycosaminoglycans. Required for proper brain and neuronal development.

1. Egger, S. et al. (2011) The Journal of biological chemistry 286, 23877-87. PMID: 21502315
2. Sennett, NC. et al. (2011) Biochemistry 50, 9651-63. PMID: 21961565
3. Egger, S. et al. (2012) The Journal of biological chemistry 287, 2119-29. PMID: 22123821
4. Sennett, NC. et al. (2012) Biochemistry 51, 9364-74. PMID: 23106432
5. Kadirvelraj, R. et al. (2014) Biochemistry 53, 8043-51. PMID: 25478983
6. Beattie, NR. et al. (2017) Biochemistry 56, 202-211. PMID: 27966912
7. Keul, ND. et al. (2018) Nature 563, 584-588. PMID: 30420606
8. Beattie, NR. et al. (2018) Biochemistry 57, 6848-6859. PMID: 30457329
9. Hengel, H. et al. (2020) Nature communications 11, 595. PMID: 32001716
Note For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human UGDH Polyclonal Antibody

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