

| Catalog No. | HD525014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human UGT8 Polyclonal Antibody (HD525014) is a rabbit polyclonal antibody detecting UGT8. Suitable for Mouse, Human, and Rat.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human UGT8 (Ala21-Gln471). | ||||||||
| Target | 2-hydroxyacylsphingosine 1-beta-galactosyltransferase, CGT, Ceramide UDP-galactosyltransferase, Cerebroside synthase, EC:2.4.1.47, UDP-galactose-ceramide galactosyltransferase, UGT4, UGT8 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q16880 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | 2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8) is a ~61 kDa protein. Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system. Galactosylates both hydroxy- and non-hydroxy fatty acid-containing ceramides and diglycerides. 1. Kapitonov, D. et al. (1997) Biochemical and biophysical research communications 232, 449-53. PMID: 9125199 | ||||||||
| Note | For research use only |
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