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Anti-Human USP34 Polyclonal Antibody (HD622014)

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Overview
Catalog No.HD622014
Description
Anti-Human USP34 Polyclonal Antibody (HD622014) is a rabbit polyclonal antibody detecting USP34. Suitable for Human and Mouse.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human USP34 (Val1894-Met2239).
Target Deubiquitinating enzyme 34, EC:3.4.19.12, KIAA0570, KIAA0729, USP34, Ubiquitin carboxyl-terminal hydrolase 34, Ubiquitin thioesterase 34, Ubiquitin-specific-processing protease 34
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q70CQ2
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Ubiquitin carboxyl-terminal hydrolase 34 (USP34) is a ~404 kDa protein. Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.

Note For research use only
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Anti-Human USP34 Polyclonal Antibody

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