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Anti-Human USP8 Polyclonal Antibody (HW322014)

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Overview
Catalog No.HW322014
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human USP8 (Lys180-Arg323).
Target Ubiquitin-specific-processing protease 8, Deubiquitinating enzyme 8, Ubiquitin carboxyl-terminal hydrolase 8, Ubiquitin isopeptidase Y, KIAA0055, USP8, UBPY, hUBPy, Ubiquitin thioesterase 8
Purification Purified by antigen affinity column.
Accession P40818
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Ubiquitin carboxyl-terminal hydrolase 8 (USP8) is a ~127 kDa protein. Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell proliferation. Required to enter into S phase in response to serum stimulation.

1. Yeates, EF. et al. (2016) The Journal of biological chemistry 291, 15753-66. PMID: 27302062
Note For research use only.
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Formula
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Anti-Human USP8 Polyclonal Antibody

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