Anti-Human VASH2/Vasohibin-2 Recombinant Antibody (SAA1602) (HP280013)

Name: Anti-Human VASH2/Vasohibin-2 Recombinant Antibody (SAA1602)
Brand: abinScience
SKU: HP280013
Price: 196 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HP280013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1602

Clonality

Monoclonal

Target

VASHL, Vasohibin-2, VASH2, Vasohibin-like protein, Tubulinyl-Tyr carboxypeptidase 2

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q86V25

RRID

Anti-Human VASH2/Vasohibin-2 Antibody (SAA1602) (abinScience Cat# HP280013, RRID:AB_3727363)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Tubulinyl-Tyr carboxypeptidase 2 (VASH2/Vasohibin-2) is a ~40 kDa protein. Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function. Critical for spindle function and accurate chromosome segregation during mitosis since microtubule detyronisation regulates mitotic spindle length and postioning. Acts as an activator of angiogenesis: expressed in infiltrating mononuclear cells in the sprouting front to promote angiogenesis. Plays a role in axon formation.

1. Nieuwenhuis, J. et al. (2017) Science (New York, N.Y.) 358, 1453-1456. PMID: 29146869

2. Liao, S. et al. (2019) Cell research 29, 533-547. PMID: 31171830

3. Kimura, H. et al. (2009) Blood 113, 4810-8. PMID: 19204325

4. Wang, N. et al. (2019) Nature structural & molecular biology 26, 571-582. PMID: 31235911

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human VASH2/Vasohibin-2 Antibody (SAA1602)

References

Datasheet

Anti-Human VASH2/Vasohibin-2 Recombinant Antibody (SAA1602).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human VASH2/Vasohibin-2 Recombinant Antibody (SAA1602) (HP280013)

Overview

Images

References

Datasheet

SDS

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