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Anti-Human WAPL Polyclonal Antibody (HD137014)

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Overview
Catalog No.HD137014
Description
Anti-Human WAPL Polyclonal Antibody (HD137014) is a rabbit polyclonal antibody detecting WAPL. Suitable for Human and Mouse.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human WAPL (His641-Asp838).
Target FOE, Friend of EBNA2 protein, KIAA0261, WAPAL, WAPL, WAPL cohesin release factor, Wings apart-like protein homolog
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q7Z5K2
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Wings apart-like protein homolog (WAPL) is a ~132 kDa protein. Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Involved in both sister chromatid cohesion during interphase and sister-chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.

1. Yeh, C. et al. (2015) Current biology : CB 25, 2290-9. PMID: 26299517
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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C₂ (Working Conc.)
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Anti-Human WAPL Polyclonal Antibody

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