

| Catalog No. | HD157014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human WDFY4 Polyclonal Antibody (HD157014) is a rabbit polyclonal antibody detecting WDFY4. Suitable for Human.
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human WDFY4 (Met2863-Gly3184). | ||||||||
| Target | C10orf64, KIAA1607, WD repeat- and FYVE domain-containing protein 4, WDFY4 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q6ZS81 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | WD repeat- and FYVE domain-containing protein 4 (WDFY4) is a ~353 kDa protein. Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells. Mechanistically, acts near the plasma membrane and interacts with endosomal membranes to promote endosomal-to-cytosol antigen trafficking. Also plays a role in B-cell survival through regulation of autophagy. | ||||||||
| Note | For research use only |
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