Anti-Human WNT1 Polyclonal Antibody (HY026014)

Name: Anti-Human WNT1 Polyclonal Antibody
Brand: abinScience
SKU: HY026014
Price: 168 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

50ug
100ug

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HY026014

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human WNT1 (Gly32-Arg255).

Target

WNT1, Proto-oncogene Wnt-1, INT1, Proto-oncogene Int-1 homolog

Purification

Purified by antigen affinity column.

Accession

P04628

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Proto-oncogene Wnt-1 (WNT1) is a ~40 kDa protein. Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Plays an essential role in the development of the embryonic brain and central nervous system (CNS). Has a role in osteoblast function, bone development and bone homeostasis.

1. Keupp, K. et al. (2013) American journal of human genetics 92, 565-74. PMID: 23499309

2. Laine, CM. et al. (2013) The New England journal of medicine 368, 1809-16. PMID: 23656646

3. Mihara, E. et al. (2016) eLife 5. PMID: 26902720

4. Won, JY. et al. (2017) European journal of medical genetics 60, 411-415. PMID: 28528193

Note

For research use only.

Images

References

Datasheet

Anti-Human WNT1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human WNT1 Polyclonal Antibody (HY026014)

Overview

Images

References

Datasheet

SDS

Quick access

Contact Us