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Anti-Human XAF1 Polyclonal Antibody (HB523014)

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Overview
Catalog No.HB523014
Description
Anti-Human XAF1 Polyclonal Antibody (HB523014) is a rabbit polyclonal antibody detecting XIAP-associated factor 1; BIRC4-binding protein; XAF1; BIRC4BP; XIAPAF1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant human XAF1 (Met1-Asp175).
Target XIAP-associated factor 1; BIRC4-binding protein; XAF1; BIRC4BP; XIAPAF1
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q6GPH4
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

XIAP-associated factor 1 (XAF1) is a ~34 kDa protein. Seems to function as a negative regulator of members of the IAP (inhibitor of apoptosis protein) family. Inhibits anti-caspase activity of BIRC4. Induces cleavage and inactivation of BIRC4 independent of caspase activation. Mediates TNF-induced apoptosis and is involved in apoptosis in trophoblast cells. May inhibit BIRC4 indirectly by activating the mitochondrial apoptosis pathway.

Note For research use only
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Formula
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Anti-Human XAF1 Polyclonal Antibody

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