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Anti-Human ZFYVE20 Recombinant Antibody (C19) (HA989023)

Anti-Human ZFYVE20 Recombinant Antibody (C19)
Anti-Human ZFYVE20 Recombinant Antibody (C19)
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Overview
Catalog No.HA989023
Species reactivityHuman
ApplicationsELISA, IF, IP
Host speciesMouse
ClonalityMonoclonal
IsotypeIgG2a, kappa
Clone IDC19
Target RBSN, ZFYVE20, Rabenosyn-5, 110 kDa protein, FYVE finger-containing Rab5 effector protein rabenosyn-5, RAB effector RBSN, Zinc finger FYVE domain-containing protein 20
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q9H1K0
RRID

Anti-Human ZFYVE20 Antibody (C19) (abinScience Cat# HA989023, RRID:AB_3729222)
_x005F_x005F_x000D_

Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Rabenosyn-5 (RBSN) is a ~88 kDa protein. Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3).

1. Nielsen, E. et al. (2000) The Journal of cell biology 151, 601-12. PMID: 11062261
2. de Renzis, S. et al. (2002) Nature cell biology 4, 124-33. PMID: 11788822
3. Naslavsky, N. et al. (2004) Molecular biology of the cell 15, 2410-22. PMID: 15020713
4. Navaroli, DM. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, E471-80. PMID: 22308388
Note For research use only.
Images
  • Anti-Human ZFYVE20 Recombinant Antibody (C19)

    SDS-PAGE

    SDS-PAGE for Anti-Human ZFYVE20 Antibody (C19)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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