Anti-Human ZFYVE27 Polyclonal Antibody (HP941014)

Name: Anti-Human ZFYVE27 Polyclonal Antibody
Brand: abinScience
SKU: HP941014
Price: 168 USD
Availability: InStock

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SDS

Overview

Catalog No.

HP941014

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant Human ZFYVE27 (Lys361-Lys411).

Target

Spastic paraplegia 33 protein, SPG33, ZFYVE27, Protrudin, Zinc finger FYVE domain-containing protein 27

Purification

Purified by antigen affinity column.

Accession

Q5T4F4

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Protrudin (ZFYVE27) is a ~45 kDa protein. Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport. Promotes axonal elongation and contributes to the establishment of neuronal cell polarity. Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner. Contributes to both the formation and stabilization of the tubular ER network. Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections.

1. Shirane, M. et al. (2006) Science (New York, N.Y.) 314, 818-21. PMID: 17082457

2. Saita, S. et al. (2009) The Journal of biological chemistry 284, 13766-13777. PMID: 19289470

3. Hashimoto, Y. et al. (2014) The Journal of biological chemistry 289, 12946-61. PMID: 24668814

4. Chang, J. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 14954-9. PMID: 23969831

5. Matsuzaki, F. et al. (2011) Molecular biology of the cell 22, 4602-20. PMID: 21976701

Note

For research use only.

Images

References

Datasheet

Anti-Human ZFYVE27 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Assay Kits

Anti-Human ZFYVE27 Polyclonal Antibody (HP941014)

Overview

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References

Datasheet

SDS

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