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Anti-Human ZHX2 Polyclonal Antibody (HP989014)

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Overview
Catalog No.HP989014
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human ZHX2 (Lys446-Arg520).
Target ZHX2, Alpha-fetoprotein regulator 1, AFR1, RAF, AFP regulator 1, Zinc finger and homeodomain protein 2, KIAA0854, Zinc fingers and homeoboxes protein 2, Regulator of AFP
Purification Purified by antigen affinity column.
Accession Q9Y6X8
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Zinc fingers and homeoboxes protein 2 (ZHX2) is a ~92 kDa protein. Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA. May play a role in retinal development where it regulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells. In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex.

1. Kawata, H. et al. (2003) The Biochemical journal 373, 747-57. PMID: 12741956
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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