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Anti-Human ZKSCAN3 Polyclonal Antibody (HP537014)

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Overview
Catalog No.HP537014
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human ZKSCAN3 (Gly41-Gly176).
Target ZNF309, Zinc finger protein 47 homolog, ZKSCAN3, Zfp-47, Zinc finger protein 306, ZSCAN13, ZNF306, Zinc finger protein 309, Zf47, ZFP47, Zinc finger protein with KRAB and SCAN domains 3, Zinc finger and SCAN domain-containing protein 13
Purification Purified by antigen affinity column.
Accession Q9BRR0
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Zinc finger protein with KRAB and SCAN domains 3 (ZKSCAN3) is a ~60 kDa protein. Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas.

Note For research use only.
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Formula
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Anti-Human ZKSCAN3 Polyclonal Antibody

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