

| Catalog No. | HT432014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human ZNF263 Polyclonal Antibody (HT432014) is a rabbit polyclonal antibody detecting ZNF263 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human ZNF263 (Lys375-Tyr546). | ||||||||
| Target | Zinc finger protein 263, Zinc finger protein FPM315, Zinc finger protein with KRAB and SCAN domains 12, ZNF263, FPM315, ZKSCAN12 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O14978 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Zinc finger protein 263 (ZNF263) is a ~77 kDa protein. Transcription factor that binds to the consensus sequence 5'-TCCTCCC-3' and acts as a transcriptional repressor. Binds to the promoter region of SIX3 and recruits other proteins involved in chromatin modification and transcriptional corepression, resulting in methylation of the promoter and transcriptional repression. Acts as a transcriptional repressor of HS3ST1 and HS3ST3A1 via binding to gene promoter regions. 1. Yu, Z. et al. (2020) Oncogene 39, 3163-3178. PMID: 32051553 2. Weiss, RJ. et al. (2020) Proceedings of the National Academy of Sciences of the United States of America 117, 9311-9317. PMID: 32277030 | ||||||||
| Note | For research use only. |
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