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Anti-Human ZNF827 Polyclonal Antibody (HD261014)

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Overview
Catalog No.HD261014
Description
Anti-Human ZNF827 Polyclonal Antibody (HD261014) is a rabbit polyclonal antibody detecting ZNF827. Suitable for Mouse and Human.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human ZNF827 (Ser809-Gly954).
Target ZNF827, Zinc finger protein 827
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q17R98
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Zinc finger protein 827 (ZNF827) is a ~119 kDa protein. As part of a ribonucleoprotein complex composed at least of HNRNPK, HNRNPL and the circular RNA circZNF827 that nucleates the complex on chromatin, may negatively regulate the transcription of genes involved in neuronal differentiation. Could also recruit the nucleosome remodeling and histone deacetylase/NuRD complex to telomeric regions of chromosomes to regulate chromatin remodeling as part of telomere maintenance.

1. Hollensen, AK. et al. (2020) eLife 9. PMID: 33174841
2. Conomos, D. et al. (2014) Nature structural & molecular biology 21, 760-70. PMID: 25150861
Note For research use only
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Datasheet
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Formula
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Anti-Human ZNF827 Polyclonal Antibody

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